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Pyrin- and CARD-only Proteins as Regulators of NLR Functions

Upon activation Nod-like receptors (NLRs) assemble into multi-protein complexes such as the NODosome and inflammasome. This process relies upon homo domain interactions between the structurally related Pyrin and caspase-recruitment (CARD) domains and adaptor proteins, such as ASC, or effector protei...

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Detalles Bibliográficos
Autores principales:	Le, Hongnga T., Harton, Jonathan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775265/ https://www.ncbi.nlm.nih.gov/pubmed/24062743 http://dx.doi.org/10.3389/fimmu.2013.00275

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