Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines

Purpose: Glioblastoma multiforme (GBM) is an aggressive primary brain tumor that is radio-resistant and recurs despite aggressive surgery, chemo, and radiotherapy. Autotaxin (ATX) is over expressed in various cancers including GBM and is implicated in tumor progression, invasion, and angiogenesis. U...

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Detalles Bibliográficos
Autores principales: Bhave, Sandeep R., Dadey, David Y. A., Karvas, Rowan M., Ferraro, Daniel J., Kotipatruni, Rama P., Jaboin, Jerry J., Hallahan, Andrew N., DeWees, Todd A., Linkous, Amanda G., Hallahan, Dennis E., Thotala, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775313/
https://www.ncbi.nlm.nih.gov/pubmed/24062988
http://dx.doi.org/10.3389/fonc.2013.00236

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