Central Role of the Gut Epithelial Barrier in the Pathogenesis of Chronic Intestinal Inflammation: Lessons Learned from Animal Models and Human Genetics

The gut mucosa is constantly challenged by a bombardment of foreign antigens and environmental microorganisms. As such, the precise regulation of the intestinal barrier allows the maintenance of mucosal immune homeostasis and prevents the onset of uncontrolled inflammation. In support of this concep...

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Detalles Bibliográficos
Autores principales: Pastorelli, Luca, De Salvo, Carlo, Mercado, Joseph R., Vecchi, Maurizio, Pizarro, Theresa T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775315/
https://www.ncbi.nlm.nih.gov/pubmed/24062746
http://dx.doi.org/10.3389/fimmu.2013.00280

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