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Models of Abnormal Scarring

Keloids and hypertrophic scars are thick, raised dermal scars, caused by derailing of the normal scarring process. Extensive research on such abnormal scarring has been done; however, these being refractory disorders specific to humans, it has been difficult to establish a universal animal model. A...

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Detalles Bibliográficos
Autores principales: Seo, Bommie F., Lee, Jun Yong, Jung, Sung-No
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775400/
https://www.ncbi.nlm.nih.gov/pubmed/24078916
http://dx.doi.org/10.1155/2013/423147
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author Seo, Bommie F.
Lee, Jun Yong
Jung, Sung-No
author_facet Seo, Bommie F.
Lee, Jun Yong
Jung, Sung-No
author_sort Seo, Bommie F.
collection PubMed
description Keloids and hypertrophic scars are thick, raised dermal scars, caused by derailing of the normal scarring process. Extensive research on such abnormal scarring has been done; however, these being refractory disorders specific to humans, it has been difficult to establish a universal animal model. A wide variety of animal models have been used. These include the athymic mouse, rats, rabbits, and pigs. Although these models have provided valuable insight into abnormal scarring, there is currently still no ideal model. This paper reviews the models that have been developed.
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spelling pubmed-37754002013-09-29 Models of Abnormal Scarring Seo, Bommie F. Lee, Jun Yong Jung, Sung-No Biomed Res Int Review Article Keloids and hypertrophic scars are thick, raised dermal scars, caused by derailing of the normal scarring process. Extensive research on such abnormal scarring has been done; however, these being refractory disorders specific to humans, it has been difficult to establish a universal animal model. A wide variety of animal models have been used. These include the athymic mouse, rats, rabbits, and pigs. Although these models have provided valuable insight into abnormal scarring, there is currently still no ideal model. This paper reviews the models that have been developed. Hindawi Publishing Corporation 2013 2013-09-03 /pmc/articles/PMC3775400/ /pubmed/24078916 http://dx.doi.org/10.1155/2013/423147 Text en Copyright © 2013 Bommie F. Seo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Seo, Bommie F.
Lee, Jun Yong
Jung, Sung-No
Models of Abnormal Scarring
title Models of Abnormal Scarring
title_full Models of Abnormal Scarring
title_fullStr Models of Abnormal Scarring
title_full_unstemmed Models of Abnormal Scarring
title_short Models of Abnormal Scarring
title_sort models of abnormal scarring
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775400/
https://www.ncbi.nlm.nih.gov/pubmed/24078916
http://dx.doi.org/10.1155/2013/423147
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