Cargando…
Models of Abnormal Scarring
Keloids and hypertrophic scars are thick, raised dermal scars, caused by derailing of the normal scarring process. Extensive research on such abnormal scarring has been done; however, these being refractory disorders specific to humans, it has been difficult to establish a universal animal model. A...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775400/ https://www.ncbi.nlm.nih.gov/pubmed/24078916 http://dx.doi.org/10.1155/2013/423147 |
_version_ | 1782477375096750080 |
---|---|
author | Seo, Bommie F. Lee, Jun Yong Jung, Sung-No |
author_facet | Seo, Bommie F. Lee, Jun Yong Jung, Sung-No |
author_sort | Seo, Bommie F. |
collection | PubMed |
description | Keloids and hypertrophic scars are thick, raised dermal scars, caused by derailing of the normal scarring process. Extensive research on such abnormal scarring has been done; however, these being refractory disorders specific to humans, it has been difficult to establish a universal animal model. A wide variety of animal models have been used. These include the athymic mouse, rats, rabbits, and pigs. Although these models have provided valuable insight into abnormal scarring, there is currently still no ideal model. This paper reviews the models that have been developed. |
format | Online Article Text |
id | pubmed-3775400 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37754002013-09-29 Models of Abnormal Scarring Seo, Bommie F. Lee, Jun Yong Jung, Sung-No Biomed Res Int Review Article Keloids and hypertrophic scars are thick, raised dermal scars, caused by derailing of the normal scarring process. Extensive research on such abnormal scarring has been done; however, these being refractory disorders specific to humans, it has been difficult to establish a universal animal model. A wide variety of animal models have been used. These include the athymic mouse, rats, rabbits, and pigs. Although these models have provided valuable insight into abnormal scarring, there is currently still no ideal model. This paper reviews the models that have been developed. Hindawi Publishing Corporation 2013 2013-09-03 /pmc/articles/PMC3775400/ /pubmed/24078916 http://dx.doi.org/10.1155/2013/423147 Text en Copyright © 2013 Bommie F. Seo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Seo, Bommie F. Lee, Jun Yong Jung, Sung-No Models of Abnormal Scarring |
title | Models of Abnormal Scarring |
title_full | Models of Abnormal Scarring |
title_fullStr | Models of Abnormal Scarring |
title_full_unstemmed | Models of Abnormal Scarring |
title_short | Models of Abnormal Scarring |
title_sort | models of abnormal scarring |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775400/ https://www.ncbi.nlm.nih.gov/pubmed/24078916 http://dx.doi.org/10.1155/2013/423147 |
work_keys_str_mv | AT seobommief modelsofabnormalscarring AT leejunyong modelsofabnormalscarring AT jungsungno modelsofabnormalscarring |