Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology

Studying the action of mechanisms of type I interferon (IFN) provides the insight to elucidate the cause and therapy for autoimmune diseases. There are high IFN responses in some diseases such as connective tissue diseases, but low responses in multiple sclerosis. Distinct IFN features lead us to un...

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Detalles Bibliográficos
Autores principales: Reder, Anthony T., Feng, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775461/
https://www.ncbi.nlm.nih.gov/pubmed/24062747
http://dx.doi.org/10.3389/fimmu.2013.00281
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author Reder, Anthony T.
Feng, Xuan
author_facet Reder, Anthony T.
Feng, Xuan
author_sort Reder, Anthony T.
collection PubMed
description Studying the action of mechanisms of type I interferon (IFN) provides the insight to elucidate the cause and therapy for autoimmune diseases. There are high IFN responses in some diseases such as connective tissue diseases, but low responses in multiple sclerosis. Distinct IFN features lead us to understand pathology of a spectrum of autoimmune diseases and help us to search genetic changes, gene expression, and biomarkers for diagnosis, disease progression, and treatment response.
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spelling pubmed-37754612013-09-23 Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology Reder, Anthony T. Feng, Xuan Front Immunol Immunology Studying the action of mechanisms of type I interferon (IFN) provides the insight to elucidate the cause and therapy for autoimmune diseases. There are high IFN responses in some diseases such as connective tissue diseases, but low responses in multiple sclerosis. Distinct IFN features lead us to understand pathology of a spectrum of autoimmune diseases and help us to search genetic changes, gene expression, and biomarkers for diagnosis, disease progression, and treatment response. Frontiers Media S.A. 2013-09-17 /pmc/articles/PMC3775461/ /pubmed/24062747 http://dx.doi.org/10.3389/fimmu.2013.00281 Text en Copyright © 2013 Reder and Feng. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Reder, Anthony T.
Feng, Xuan
Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology
title Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology
title_full Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology
title_fullStr Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology
title_full_unstemmed Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology
title_short Aberrant Type I Interferon Regulation in Autoimmunity: Opposite Directions in MS and SLE, Shaped by Evolution and Body Ecology
title_sort aberrant type i interferon regulation in autoimmunity: opposite directions in ms and sle, shaped by evolution and body ecology
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775461/
https://www.ncbi.nlm.nih.gov/pubmed/24062747
http://dx.doi.org/10.3389/fimmu.2013.00281
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