Cargando…
High-Density Lipoprotein and Prostate Cancer: An Overview
Prostate cancer is a common disease in modern, developed societies and has a high incidence and mortality. High-density lipoprotein cholesterol (HDL-C) has recently received much attention as a possible risk marker of prostate cancer development and prognosis. In the present article, we summarized f...
Formato: | Online Artículo Texto |
---|---|
Lenguaje: | English |
Publicado: |
Japan Epidemiological Association
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775524/ https://www.ncbi.nlm.nih.gov/pubmed/23985823 http://dx.doi.org/10.2188/jea.JE20130006 |
_version_ | 1782477390187855872 |
---|---|
collection | PubMed |
description | Prostate cancer is a common disease in modern, developed societies and has a high incidence and mortality. High-density lipoprotein cholesterol (HDL-C) has recently received much attention as a possible risk marker of prostate cancer development and prognosis. In the present article, we summarized findings from epidemiologic studies of the association between HDL-C and prostate cancer. Low HDL-C level was found to be a risk and prognostic factor of prostate cancer in several epidemiologic studies, although the overall linkage between HDL and prostate cancer has not been definitively established. The mechanisms for this association remain uncertain; however, limited data from experimental studies imply a possible role of HDL in the pathophysiology of prostate cancer. More epidemiologic research, in combination with experimental studies, is needed in this field. |
format | Online Article Text |
id | pubmed-3775524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Japan Epidemiological Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-37755242013-11-18 High-Density Lipoprotein and Prostate Cancer: An Overview J Epidemiol Review Article Prostate cancer is a common disease in modern, developed societies and has a high incidence and mortality. High-density lipoprotein cholesterol (HDL-C) has recently received much attention as a possible risk marker of prostate cancer development and prognosis. In the present article, we summarized findings from epidemiologic studies of the association between HDL-C and prostate cancer. Low HDL-C level was found to be a risk and prognostic factor of prostate cancer in several epidemiologic studies, although the overall linkage between HDL and prostate cancer has not been definitively established. The mechanisms for this association remain uncertain; however, limited data from experimental studies imply a possible role of HDL in the pathophysiology of prostate cancer. More epidemiologic research, in combination with experimental studies, is needed in this field. Japan Epidemiological Association 2013-09-05 /pmc/articles/PMC3775524/ /pubmed/23985823 http://dx.doi.org/10.2188/jea.JE20130006 Text en © 2013 Kazuhiko Kotani et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Review Article High-Density Lipoprotein and Prostate Cancer: An Overview |
title | High-Density Lipoprotein and Prostate Cancer: An Overview |
title_full | High-Density Lipoprotein and Prostate Cancer: An Overview |
title_fullStr | High-Density Lipoprotein and Prostate Cancer: An Overview |
title_full_unstemmed | High-Density Lipoprotein and Prostate Cancer: An Overview |
title_short | High-Density Lipoprotein and Prostate Cancer: An Overview |
title_sort | high-density lipoprotein and prostate cancer: an overview |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775524/ https://www.ncbi.nlm.nih.gov/pubmed/23985823 http://dx.doi.org/10.2188/jea.JE20130006 |
work_keys_str_mv | AT highdensitylipoproteinandprostatecanceranoverview AT highdensitylipoproteinandprostatecanceranoverview AT highdensitylipoproteinandprostatecanceranoverview AT highdensitylipoproteinandprostatecanceranoverview AT highdensitylipoproteinandprostatecanceranoverview AT highdensitylipoproteinandprostatecanceranoverview |