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Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines
Tumor relapse after radiotherapy is a great concern in the treatment of high-grade gliomas. Inhibition of the PI3-kinase/AKT pathway is known to radiosensitize cancer cells and to delay their DNA repair after irradiation. In this study, we show that the radiosensitization of CB193 and T98G, two high...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775596/ https://www.ncbi.nlm.nih.gov/pubmed/23727752 http://dx.doi.org/10.3892/ijo.2013.1970 |