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Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines

Tumor relapse after radiotherapy is a great concern in the treatment of high-grade gliomas. Inhibition of the PI3-kinase/AKT pathway is known to radiosensitize cancer cells and to delay their DNA repair after irradiation. In this study, we show that the radiosensitization of CB193 and T98G, two high...

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Detalles Bibliográficos
Autores principales:	MILLET, P., GRANOTIER, C., ETIENNE, O., BOUSSIN, F.D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775596/ https://www.ncbi.nlm.nih.gov/pubmed/23727752 http://dx.doi.org/10.3892/ijo.2013.1970

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