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Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes
Background. RNA editing is a post-transcriptional regulatory mechanism that can alter the coding sequences of certain genes in response to physiological demands. We previously identified C-to-U RNA editing (C136U, R46X) which inactivates a small fraction of succinate dehydrogenase (SDH; mitochondria...
Autores principales: | Baysal, Bora E., De Jong, Kitty, Liu, Biao, Wang, Jianmin, Patnaik, Santosh K., Wallace, Paul K., Taggart, Robert T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775634/ https://www.ncbi.nlm.nih.gov/pubmed/24058882 http://dx.doi.org/10.7717/peerj.152 |
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