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Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action and the binding site on the β(2) subunit of GABA(A) receptors?

NA-glycine is an endogenous lipid molecule with analgesic properties, which is structurally similar to the endocannabinoids 2-AG and anandamide but does not interact with cannabinoid receptors. NA-glycine has been suggested to act at the G-protein coupled receptors GPR18 and GPR92. Recently, we have...

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Detalles Bibliográficos
Autores principales: Baur, Roland, Gertsch, Jürg, Sigel, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775635/
https://www.ncbi.nlm.nih.gov/pubmed/24058880
http://dx.doi.org/10.7717/peerj.149

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