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Evidence for DNA Cleavage Caused Directly by a transfer RNA-Targeting Toxin

The killer yeast species Pichia acaciae produces a heteromeric killer protein, PaT, that causes DNA damage and arrests the cell cycle of sensitive Saccharomyces cerevisiae in the S phase. However, the mechanism by which DNA damage occurs remains elusive. A previous study has indicated that Orf2p, a...

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Detalles Bibliográficos
Autores principales:	Shigematsu, Megumi, Ogawa, Tetsuhiro, Tanaka, Wataru, Takahashi, Kazutoshi, Kitamoto, Hiroko K., Hidaka, Makoto, Masaki, Haruhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775755/ https://www.ncbi.nlm.nih.gov/pubmed/24069426 http://dx.doi.org/10.1371/journal.pone.0075512

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