Combined Inhibition of p97 and the Proteasome Causes Lethal Disruption of the Secretory Apparatus in Multiple Myeloma Cells

Inhibition of the proteasome is a widely used strategy for treating multiple myeloma that takes advantage of the heavy secretory load that multiple myeloma cells (MMCs) have to deal with. Resistance of MMCs to proteasome inhibition has been linked to incomplete disruption of proteasomal endoplasmic-...

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Detalles Bibliográficos
Autores principales: Auner, Holger W., Moody, Anne Marie, Ward, Theresa H., Kraus, Marianne, Milan, Enrico, May, Philippa, Chaidos, Aristeidis, Driessen, Christoph, Cenci, Simone, Dazzi, Francesco, Rahemtulla, Amin, Apperley, Jane F., Karadimitris, Anastasios, Dillon, Niall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775786/
https://www.ncbi.nlm.nih.gov/pubmed/24069311
http://dx.doi.org/10.1371/journal.pone.0074415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775786/
https://www.ncbi.nlm.nih.gov/pubmed/24069311
http://dx.doi.org/10.1371/journal.pone.0074415

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