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Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis
Calcium signaling in the brain is fundamental to the learning and memory process and there is evidence to suggest that its dysfunction is involved in the pathological pathways underlying Alzheimer’s disease (AD). Recently, the calcium hypothesis of AD has received support with the identification of...
Autores principales: | Rubio-Moscardo, Fanny, Setó-Salvia, Núria, Pera, Marta, Bosch-Morató, Mònica, Plata, Cristina, Belbin, Olivia, Gené, Gemma, Dols-Icardo, Oriol, Ingelsson, Martin, Helisalmi, Seppo, Soininen, Hilkka, Hiltunen, Mikko, Giedraitis, Vilmantas, Lannfelt, Lars, Frank, Ana, Bullido, MªJesús, Combarros, Onofre, Sánchez-Juan, Pascual, Boada, Mercè, Tárraga, Lluís, Pastor, Pau, Pérez-Tur, Jordi, Baquero, Miquel, Molinuevo, José L., Sánchez-Valle, Raquel, Fuentes-Prior, Pablo, Fortea, Juan, Blesa, Rafael, Muñoz, Francisco J., Lleó, Alberto, Valverde, Miguel A., Clarimón, Jordi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775809/ https://www.ncbi.nlm.nih.gov/pubmed/24069280 http://dx.doi.org/10.1371/journal.pone.0074203 |
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