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Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice
Paradoxical seizure exacerbation by anti-epileptic medication is a well-known clinical phenomenon in epilepsy, but the cellular mechanisms remain unclear. One possibility is enhanced network disinhibition by unintended suppression of inhibitory interneurons. We investigated this hypothesis in the st...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776135/ https://www.ncbi.nlm.nih.gov/pubmed/24065886 http://dx.doi.org/10.3389/fncel.2013.00156 |