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Contemporary role of medical genetics in internal medicine
Molecular biology and medical genetics, one of the most dynamically developing fields of medicine, nowadays is also a base for development of basic and clinical research in internal medicine. Understanding of crucial genetic pathomechanisms of many common diseases was possible due to the newest and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776171/ https://www.ncbi.nlm.nih.gov/pubmed/24049516 http://dx.doi.org/10.5114/aoms.2013.34988 |
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author | Saracyn, Marek Płoski, Rafał Niemczyk, Stanisław |
author_facet | Saracyn, Marek Płoski, Rafał Niemczyk, Stanisław |
author_sort | Saracyn, Marek |
collection | PubMed |
description | Molecular biology and medical genetics, one of the most dynamically developing fields of medicine, nowadays is also a base for development of basic and clinical research in internal medicine. Understanding of crucial genetic pathomechanisms of many common diseases was possible due to the newest and modern molecular methods and tools. Moreover, development of genetics also made possible the discovery and understanding of the pathogenesis of many different diseases. However, not so long ago, we discovered precise pathomechanisms leading from damage of a single gene to a related pathological phenotype. Now, we have just started to explain molecular mechanisms of complex, multifactorial diseases. To achieve these goals, we need permanent development of genetic tests, genomics and proteomics. After fulfilling these conditions, we will get a chance to implement all molecular and genetic hopes, particularly their practical application in the clinic. |
format | Online Article Text |
id | pubmed-3776171 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-37761712013-09-18 Contemporary role of medical genetics in internal medicine Saracyn, Marek Płoski, Rafał Niemczyk, Stanisław Arch Med Sci State of the Art Paper Molecular biology and medical genetics, one of the most dynamically developing fields of medicine, nowadays is also a base for development of basic and clinical research in internal medicine. Understanding of crucial genetic pathomechanisms of many common diseases was possible due to the newest and modern molecular methods and tools. Moreover, development of genetics also made possible the discovery and understanding of the pathogenesis of many different diseases. However, not so long ago, we discovered precise pathomechanisms leading from damage of a single gene to a related pathological phenotype. Now, we have just started to explain molecular mechanisms of complex, multifactorial diseases. To achieve these goals, we need permanent development of genetic tests, genomics and proteomics. After fulfilling these conditions, we will get a chance to implement all molecular and genetic hopes, particularly their practical application in the clinic. Termedia Publishing House 2013-04-30 2013-08-30 /pmc/articles/PMC3776171/ /pubmed/24049516 http://dx.doi.org/10.5114/aoms.2013.34988 Text en Copyright © 2013 Termedia & Banach http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | State of the Art Paper Saracyn, Marek Płoski, Rafał Niemczyk, Stanisław Contemporary role of medical genetics in internal medicine |
title | Contemporary role of medical genetics in internal medicine |
title_full | Contemporary role of medical genetics in internal medicine |
title_fullStr | Contemporary role of medical genetics in internal medicine |
title_full_unstemmed | Contemporary role of medical genetics in internal medicine |
title_short | Contemporary role of medical genetics in internal medicine |
title_sort | contemporary role of medical genetics in internal medicine |
topic | State of the Art Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776171/ https://www.ncbi.nlm.nih.gov/pubmed/24049516 http://dx.doi.org/10.5114/aoms.2013.34988 |
work_keys_str_mv | AT saracynmarek contemporaryroleofmedicalgeneticsininternalmedicine AT płoskirafał contemporaryroleofmedicalgeneticsininternalmedicine AT niemczykstanisław contemporaryroleofmedicalgeneticsininternalmedicine |