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Contemporary role of medical genetics in internal medicine

Molecular biology and medical genetics, one of the most dynamically developing fields of medicine, nowadays is also a base for development of basic and clinical research in internal medicine. Understanding of crucial genetic pathomechanisms of many common diseases was possible due to the newest and...

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Detalles Bibliográficos
Autores principales: Saracyn, Marek, Płoski, Rafał, Niemczyk, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776171/
https://www.ncbi.nlm.nih.gov/pubmed/24049516
http://dx.doi.org/10.5114/aoms.2013.34988
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author Saracyn, Marek
Płoski, Rafał
Niemczyk, Stanisław
author_facet Saracyn, Marek
Płoski, Rafał
Niemczyk, Stanisław
author_sort Saracyn, Marek
collection PubMed
description Molecular biology and medical genetics, one of the most dynamically developing fields of medicine, nowadays is also a base for development of basic and clinical research in internal medicine. Understanding of crucial genetic pathomechanisms of many common diseases was possible due to the newest and modern molecular methods and tools. Moreover, development of genetics also made possible the discovery and understanding of the pathogenesis of many different diseases. However, not so long ago, we discovered precise pathomechanisms leading from damage of a single gene to a related pathological phenotype. Now, we have just started to explain molecular mechanisms of complex, multifactorial diseases. To achieve these goals, we need permanent development of genetic tests, genomics and proteomics. After fulfilling these conditions, we will get a chance to implement all molecular and genetic hopes, particularly their practical application in the clinic.
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spelling pubmed-37761712013-09-18 Contemporary role of medical genetics in internal medicine Saracyn, Marek Płoski, Rafał Niemczyk, Stanisław Arch Med Sci State of the Art Paper Molecular biology and medical genetics, one of the most dynamically developing fields of medicine, nowadays is also a base for development of basic and clinical research in internal medicine. Understanding of crucial genetic pathomechanisms of many common diseases was possible due to the newest and modern molecular methods and tools. Moreover, development of genetics also made possible the discovery and understanding of the pathogenesis of many different diseases. However, not so long ago, we discovered precise pathomechanisms leading from damage of a single gene to a related pathological phenotype. Now, we have just started to explain molecular mechanisms of complex, multifactorial diseases. To achieve these goals, we need permanent development of genetic tests, genomics and proteomics. After fulfilling these conditions, we will get a chance to implement all molecular and genetic hopes, particularly their practical application in the clinic. Termedia Publishing House 2013-04-30 2013-08-30 /pmc/articles/PMC3776171/ /pubmed/24049516 http://dx.doi.org/10.5114/aoms.2013.34988 Text en Copyright © 2013 Termedia & Banach http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle State of the Art Paper
Saracyn, Marek
Płoski, Rafał
Niemczyk, Stanisław
Contemporary role of medical genetics in internal medicine
title Contemporary role of medical genetics in internal medicine
title_full Contemporary role of medical genetics in internal medicine
title_fullStr Contemporary role of medical genetics in internal medicine
title_full_unstemmed Contemporary role of medical genetics in internal medicine
title_short Contemporary role of medical genetics in internal medicine
title_sort contemporary role of medical genetics in internal medicine
topic State of the Art Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776171/
https://www.ncbi.nlm.nih.gov/pubmed/24049516
http://dx.doi.org/10.5114/aoms.2013.34988
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