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Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease
BACKGROUND: The development of disease-modifying therapies for Alzheimer’s disease is hampered by our lack of understanding of the early pathogenic mechanisms and the lack of early biomarkers and risk factors. We have documented the expression pattern of mTOR regulated genes in the frontal cortex of...
Autores principales: | Yates, Sharon C, Zafar, Amen, Hubbard, Paul, Nagy, Sheila, Durant, Sarah, Bicknell, Roy, Wilcock, Gordon, Christie, Sharon, Esiri, Margaret M, Smith, A David, Nagy, Zsuzsanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776211/ https://www.ncbi.nlm.nih.gov/pubmed/24252508 http://dx.doi.org/10.1186/2051-5960-1-3 |
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