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Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties
The epithelial-mesenchymal transition (EMT) imparts metastatic competence on otherwise non-metastatic cancer cells through decreased inter-cellular adhesions, increased migratory capacity, stem cell properties and anoikis and chemotherapy resistance. In this study, we profiled changes in microRNA ex...
Autores principales: | Taube, Joseph H., Malouf, Gabriel G., Lu, Emily, Sphyris, Nathalie, Vijay, Vidya, Ramachandran, Priyanka P., Ueno, Katumasa R., Gaur, Sanchaika, Nicoloso, Milena S., Rossi, Simona, Herschkowitz, Jason I., Rosen, Jeffrey M., Issa, Jean-Pierre J., Calin, George A., Chang, Jeffrey T., Mani, Sendurai A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776231/ https://www.ncbi.nlm.nih.gov/pubmed/24045437 http://dx.doi.org/10.1038/srep02687 |
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