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Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties

The epithelial-mesenchymal transition (EMT) imparts metastatic competence on otherwise non-metastatic cancer cells through decreased inter-cellular adhesions, increased migratory capacity, stem cell properties and anoikis and chemotherapy resistance. In this study, we profiled changes in microRNA ex...

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Detalles Bibliográficos
Autores principales: Taube, Joseph H., Malouf, Gabriel G., Lu, Emily, Sphyris, Nathalie, Vijay, Vidya, Ramachandran, Priyanka P., Ueno, Katumasa R., Gaur, Sanchaika, Nicoloso, Milena S., Rossi, Simona, Herschkowitz, Jason I., Rosen, Jeffrey M., Issa, Jean-Pierre J., Calin, George A., Chang, Jeffrey T., Mani, Sendurai A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776231/
https://www.ncbi.nlm.nih.gov/pubmed/24045437
http://dx.doi.org/10.1038/srep02687

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