Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application

JAK-STAT (Janus associated kinase-signal transducer and activator of transcription) pathway plays a critical role in transduction of extracellular signals from cytokines and growth factors involved in hematopoiesis, immune regulation, fertility, lactation, growth and embryogenesis. JAK family contai...

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Detalles Bibliográficos
Autores principales: Furqan, Muhammad, Mukhi, Nikhil, Lee, Byung, Liu, Delong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776247/
https://www.ncbi.nlm.nih.gov/pubmed/24252238
http://dx.doi.org/10.1186/2050-7771-1-5

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