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SnoN facilitates ALK1–Smad1/5 signaling during embryonic angiogenesis

In endothelial cells, two type I receptors of the transforming growth factor β (TGF-β) family, ALK1 and ALK5, coordinate to regulate embryonic angiogenesis in response to BMP9/10 and TGF-β. Whereas TGF-β binds to and activates ALK5, leading to Smad2/3 phosphorylation and inhibition of endothelial ce...

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Detalles Bibliográficos
Autores principales:	Zhu, Qingwei, Kim, Yong Hwan, Wang, Douglas, Oh, S. Paul, Luo, Kunxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776356/ https://www.ncbi.nlm.nih.gov/pubmed/24019535 http://dx.doi.org/10.1083/jcb.201208113

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