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Calculating disability-adjusted-life-years lost (DALYs) in discrete-time

Disability-adjusted-life-years lost (DALYs) is a common outcome metric for cost-effectiveness analyses, and the equations used for such calculations have been presented previously by Fox-Rushby and Hanson (see, e.g., “Health Policy and Planning 16:326–331, 2001”). While the equations are clear, the...

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Autor principal: Larson, Bruce A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776440/
https://www.ncbi.nlm.nih.gov/pubmed/23927817
http://dx.doi.org/10.1186/1478-7547-11-18
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author Larson, Bruce A
author_facet Larson, Bruce A
author_sort Larson, Bruce A
collection PubMed
description Disability-adjusted-life-years lost (DALYs) is a common outcome metric for cost-effectiveness analyses, and the equations used for such calculations have been presented previously by Fox-Rushby and Hanson (see, e.g., “Health Policy and Planning 16:326–331, 2001”). While the equations are clear, the logic behind them is opaque at best for a large share of public health practitioners and students. The objective of this paper is to show how to calculate DALYs using a discrete time formulation that is easy to teach to students and public health practitioners, is easy to apply for those with basic discounting skills, and is consistent with the discounting methods typically included on the costing side of cost-effectiveness analysis. A continuous-time adjustment factor is derived that can be used to ensure exact consistency between the continuous and discrete time approaches, but this level of precision is typically unnecessary for cost-effectiveness analyses. To illustrate the approach, both a new, simple example and the same example presented in Fox-Rushby and Hanson are used throughout the paper.
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spelling pubmed-37764402013-09-19 Calculating disability-adjusted-life-years lost (DALYs) in discrete-time Larson, Bruce A Cost Eff Resour Alloc Methodology Disability-adjusted-life-years lost (DALYs) is a common outcome metric for cost-effectiveness analyses, and the equations used for such calculations have been presented previously by Fox-Rushby and Hanson (see, e.g., “Health Policy and Planning 16:326–331, 2001”). While the equations are clear, the logic behind them is opaque at best for a large share of public health practitioners and students. The objective of this paper is to show how to calculate DALYs using a discrete time formulation that is easy to teach to students and public health practitioners, is easy to apply for those with basic discounting skills, and is consistent with the discounting methods typically included on the costing side of cost-effectiveness analysis. A continuous-time adjustment factor is derived that can be used to ensure exact consistency between the continuous and discrete time approaches, but this level of precision is typically unnecessary for cost-effectiveness analyses. To illustrate the approach, both a new, simple example and the same example presented in Fox-Rushby and Hanson are used throughout the paper. BioMed Central 2013-08-08 /pmc/articles/PMC3776440/ /pubmed/23927817 http://dx.doi.org/10.1186/1478-7547-11-18 Text en Copyright © 2013 Larson; licensee BioMed Central Ltd.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Methodology
Larson, Bruce A
Calculating disability-adjusted-life-years lost (DALYs) in discrete-time
title Calculating disability-adjusted-life-years lost (DALYs) in discrete-time
title_full Calculating disability-adjusted-life-years lost (DALYs) in discrete-time
title_fullStr Calculating disability-adjusted-life-years lost (DALYs) in discrete-time
title_full_unstemmed Calculating disability-adjusted-life-years lost (DALYs) in discrete-time
title_short Calculating disability-adjusted-life-years lost (DALYs) in discrete-time
title_sort calculating disability-adjusted-life-years lost (dalys) in discrete-time
topic Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776440/
https://www.ncbi.nlm.nih.gov/pubmed/23927817
http://dx.doi.org/10.1186/1478-7547-11-18
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