MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons

Bone morphogenetic protein (BMP) signaling has emerged as an important regulator of sensory neuron development. Using a three-generation forward genetic screen in mice we have identified Megf8 as a novel modifier of BMP4 signaling in trigeminal ganglion (TG) neurons. Loss of Megf8 disrupts axon guid...

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Detalles Bibliográficos
Autores principales: Engelhard, Caitlin, Sarsfield, Sarah, Merte, Janna, Wang, Qiang, Li, Peng, Beppu, Hideyuki, Kolodkin, Alex L, Sucov, Henry M, Ginty, David D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776557/
https://www.ncbi.nlm.nih.gov/pubmed/24052814
http://dx.doi.org/10.7554/eLife.01160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776557/
https://www.ncbi.nlm.nih.gov/pubmed/24052814
http://dx.doi.org/10.7554/eLife.01160

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