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MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
Bone morphogenetic protein (BMP) signaling has emerged as an important regulator of sensory neuron development. Using a three-generation forward genetic screen in mice we have identified Megf8 as a novel modifier of BMP4 signaling in trigeminal ganglion (TG) neurons. Loss of Megf8 disrupts axon guid...
Autores principales: | Engelhard, Caitlin, Sarsfield, Sarah, Merte, Janna, Wang, Qiang, Li, Peng, Beppu, Hideyuki, Kolodkin, Alex L, Sucov, Henry M, Ginty, David D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776557/ https://www.ncbi.nlm.nih.gov/pubmed/24052814 http://dx.doi.org/10.7554/eLife.01160 |
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