Amplification of c-MYC and MLL Genes as a Marker of Clonal Cell Progression in Patients with Myeloid Malignancy and Trisomy of Chromosomes 8 or 11

Gene amplification (amp) is one of the basic mechanisms connected with overexpression of oncogenes. The c-MYC (located in 8q24) and MLL (located in 11q23) are the most often over represented genes that lead to a rapid proliferation of the affected cell clone in patients with myeloid neoplasms. Asses...

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Detalles Bibliográficos
Autores principales: Angelova, S, Jordanova, M, Spassov, B, Shivarov, V, Simeonova, M, Christov, I, Angelova, P, Alexandrova, K, Stoimenov, A, Nikolova, V, Dimova, I, Ganeva, P, Tzvetkov, N, Hadjiev, E, Toshkov, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Macedonian Science of Sciences and Arts 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776705/
https://www.ncbi.nlm.nih.gov/pubmed/24052708
http://dx.doi.org/10.2478/v10034-011-0043-y

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