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Role of poly(ADP-ribosyl)ation in a ‘two-hit’ model of hypoxia and oxidative stress in human A549 epithelial cells in vitro

A preceding hypoxic insult can sensitize the cells or the organism to a subsequent, second insult. The aim of the present study was to investigate the molecular mechanism of this phenomenon (often termed ‘two-hit’ injury paradigm), in an in vitro model of hypoxia/oxidative stress injury in A549 epit...

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Detalles Bibliográficos
Autores principales: ERDÉLYI, KATALIN, PACHER, PÁL, VIRÁG, LÁSZLÓ, SZABÓ, CSABA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776717/
https://www.ncbi.nlm.nih.gov/pubmed/23722590
http://dx.doi.org/10.3892/ijmm.2013.1397