Biodistribution and Subcellular Localization of an Unnatural Boron-Containing Amino Acid (Cis-ABCPC) by Imaging Secondary Ion Mass Spectrometry for Neutron Capture Therapy of Melanomas and Gliomas

The development of new boron-delivery agents is a high priority for improving the effectiveness of boron neutron capture therapy. In the present study, 1-amino-3-borono-cyclopentanecarboxylic acid (cis-ABCPC) as a mixture of its L- and D- enantiomers was evaluated in vivo using the B16 melanoma mode...

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Detalles Bibliográficos
Autores principales: Chandra, Subhash, Barth, Rolf F., Haider, Syed A., Yang, Weilian, Huo, Tianyao, Shaikh, Aarif L., Kabalka, George W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776788/
https://www.ncbi.nlm.nih.gov/pubmed/24058680
http://dx.doi.org/10.1371/journal.pone.0075377

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