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The Hierarchical Process of Differentiation of Long-Lived Antibody-Secreting Cells Is Dependent on Integrated Signals Derived from Antigen and IL-17A
Switched CD19-positive memory B cells purified from mice with chronic immune response against Thalassophryne nattereri venom proteins were cultured with venom or cytokines. Our results confirm the existence of a hierarchic process of differentiation: activated memory B cells progressively acquire in...
Autores principales: | Grund, Lidiane Zito, Lopes-Ferreira, Monica, Lima, Carla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776816/ https://www.ncbi.nlm.nih.gov/pubmed/24058589 http://dx.doi.org/10.1371/journal.pone.0074566 |
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