Leucine-Rich α2-Glycoprotein Is a Novel Biomarker of Neurodegenerative Disease in Human Cerebrospinal Fluid and Causes Neurodegeneration in Mouse Cerebral Cortex

Leucine-rich α2-glycoprotein (LRG) is a protein induced by inflammation. It contains a leucine-rich repeat (LRR) structure and easily binds with other molecules. However, the function of LRG in the brain during aging and neurodegenerative diseases has not been investigated. Here, we measured human L...

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Detalles Bibliográficos
Autores principales: Miyajima, Masakazu, Nakajima, Madoka, Motoi, Yumiko, Moriya, Masao, Sugano, Hidenori, Ogino, Ikuko, Nakamura, Eri, Tada, Norihiro, Kunichika, Miyuki, Arai, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776841/
https://www.ncbi.nlm.nih.gov/pubmed/24058569
http://dx.doi.org/10.1371/journal.pone.0074453

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