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The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors

Adhesion class G protein-coupled receptors (aGPCR) form the second largest group of seven-transmembrane-spanning (7TM) receptors whose molecular layout and function differ from canonical 7TM receptors. Despite their essential roles in immunity, tumorigenesis, and development, the mechanisms of aGPCR...

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Detalles Bibliográficos
Autores principales: Prömel, Simone, Frickenhaus, Marie, Hughes, Samantha, Mestek, Lamia, Staunton, David, Woollard, Alison, Vakonakis, Ioannis, Schöneberg, Torsten, Schnabel, Ralf, Russ, Andreas P., Langenhan, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776922/
https://www.ncbi.nlm.nih.gov/pubmed/22938866
http://dx.doi.org/10.1016/j.celrep.2012.06.015