S-1 plus irinotecan and oxaliplatin for the first-line treatment of patients with metastatic colorectal cancer: a prospective phase II study and pharmacogenetic analysis

BACKGROUND: S-1 is an oral fluoropyrimidine that mimics infusional 5-fluorouracil. The aim of this phase II trial was to explore the clinical efficacy of the triplet regimen TIROX, which consists of S-1, irinotecan and oxaliplatin. METHODS: Forty-two chemo-naive patients with metastatic colorectal c...

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Detalles Bibliográficos
Autores principales: Kim, S Y, S Hong, Y, K Shim, E, Kong, S-Y, Shin, A, Baek, J Y, Jung, K H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776990/
https://www.ncbi.nlm.nih.gov/pubmed/23963147
http://dx.doi.org/10.1038/bjc.2013.479

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