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A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo
The development of tools for efficient targeting of antigens to antigen presenting cells is of great importance for vaccine development. We have previously shown that fusion proteins containing antigens fused to the extra domain A from fibronectin (EDA), an endogenous TLR4 ligand, which targets anti...
Autores principales: | Arribillaga, Laura, Durantez, Maika, Lozano, Teresa, Rudilla, Francesc, Rehberger, Federico, Casares, Noelia, Villanueva, Lorea, Martinez, Marta, Gorraiz, Marta, Borrás-Cuesta, Francisco, Sarobe, Pablo, Prieto, Jesús, Lasarte, Juan José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777173/ https://www.ncbi.nlm.nih.gov/pubmed/24093105 http://dx.doi.org/10.1155/2013/864720 |
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