PDZ Domains and Viral Infection: Versatile Potentials of HPV-PDZ Interactions in relation to Malignancy

Cervical cancer is caused by high-risk human papillomaviruses (HPVs), and a unique characteristic of these is a PDZ ([Formula: see text] SD-95/ [Formula: see text] lg/ [Formula: see text] O-1-)binding motif in their E6 proteins. Through this motif HPV E6 interacts with a variety of PDZ domain-contai...

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Detalles Bibliográficos
Autores principales: Nagasaka, Kazunori, Kawana, Kei, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777178/
https://www.ncbi.nlm.nih.gov/pubmed/24093094
http://dx.doi.org/10.1155/2013/369712

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