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Schwannoma in the Upper Limbs

Schwannomas are the commonest tumours of peripheral nerves. Despite the classical description that schwannomas are well encapsulated and can be completely enucleated during excision, a portion of them have fascicular involvement and could not be completely shelled out. A retrospective review for 8 p...

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Detalles Bibliográficos
Autores principales: Yuk Kwan Tang, Chris, Fung, Boris, Fok, Margaret, Zhu, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777180/
https://www.ncbi.nlm.nih.gov/pubmed/24093090
http://dx.doi.org/10.1155/2013/167196
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author Yuk Kwan Tang, Chris
Fung, Boris
Fok, Margaret
Zhu, Janet
author_facet Yuk Kwan Tang, Chris
Fung, Boris
Fok, Margaret
Zhu, Janet
author_sort Yuk Kwan Tang, Chris
collection PubMed
description Schwannomas are the commonest tumours of peripheral nerves. Despite the classical description that schwannomas are well encapsulated and can be completely enucleated during excision, a portion of them have fascicular involvement and could not be completely shelled out. A retrospective review for 8 patients was carried out over 10 years. 75% of schwannoma occurred over the distal region of upper limb (at elbow or distal to it). It occurs more in the mixed nerve instead of pure sensory or motor nerve. 50% of patients had mixed nerve involvement. Fascicular involvement was very common in schwannoma (75% of patients). Removal of the tumour with fascicles can cause functional deficit. At present, there is no method (including preoperative MRI) which can predict the occurrence of fascicular involvement; the authors therefore proposed a new system to stratify patients who may benefit from interfascicular nerve grafts. In this group of patients, the authors strongly recommend that the possibility and option of nerve graft should be discussed with patients prior to schwannoma excision, so that nerve grafting could be directly proceeded with patient consent in case there is fascicular involvement of tumour found intraoperatively.
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spelling pubmed-37771802013-10-03 Schwannoma in the Upper Limbs Yuk Kwan Tang, Chris Fung, Boris Fok, Margaret Zhu, Janet Biomed Res Int Clinical Study Schwannomas are the commonest tumours of peripheral nerves. Despite the classical description that schwannomas are well encapsulated and can be completely enucleated during excision, a portion of them have fascicular involvement and could not be completely shelled out. A retrospective review for 8 patients was carried out over 10 years. 75% of schwannoma occurred over the distal region of upper limb (at elbow or distal to it). It occurs more in the mixed nerve instead of pure sensory or motor nerve. 50% of patients had mixed nerve involvement. Fascicular involvement was very common in schwannoma (75% of patients). Removal of the tumour with fascicles can cause functional deficit. At present, there is no method (including preoperative MRI) which can predict the occurrence of fascicular involvement; the authors therefore proposed a new system to stratify patients who may benefit from interfascicular nerve grafts. In this group of patients, the authors strongly recommend that the possibility and option of nerve graft should be discussed with patients prior to schwannoma excision, so that nerve grafting could be directly proceeded with patient consent in case there is fascicular involvement of tumour found intraoperatively. Hindawi Publishing Corporation 2013 2013-09-04 /pmc/articles/PMC3777180/ /pubmed/24093090 http://dx.doi.org/10.1155/2013/167196 Text en Copyright © 2013 Chris Yuk Kwan Tang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Yuk Kwan Tang, Chris
Fung, Boris
Fok, Margaret
Zhu, Janet
Schwannoma in the Upper Limbs
title Schwannoma in the Upper Limbs
title_full Schwannoma in the Upper Limbs
title_fullStr Schwannoma in the Upper Limbs
title_full_unstemmed Schwannoma in the Upper Limbs
title_short Schwannoma in the Upper Limbs
title_sort schwannoma in the upper limbs
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777180/
https://www.ncbi.nlm.nih.gov/pubmed/24093090
http://dx.doi.org/10.1155/2013/167196
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