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Giant cell tumor of dorsal vertebral body
A 30-year-old female patient presented with complaints of backache, weakness in both lower limbs and bladder/bowel dysfunction. Imaging showed an osteolytic lesion at tenth dorsal (D10) vertebra with anterior compression on the spinal cord. Complete intralesional tumor excision with reconstruction w...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777315/ https://www.ncbi.nlm.nih.gov/pubmed/24082687 http://dx.doi.org/10.4103/0974-8237.116542 |
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author | Redhu, Rakesh Poonia, Rajpal |
author_facet | Redhu, Rakesh Poonia, Rajpal |
author_sort | Redhu, Rakesh |
collection | PubMed |
description | A 30-year-old female patient presented with complaints of backache, weakness in both lower limbs and bladder/bowel dysfunction. Imaging showed an osteolytic lesion at tenth dorsal (D10) vertebra with anterior compression on the spinal cord. Complete intralesional tumor excision with reconstruction was carried out using the anterolateral extrapleural approach. Histopathological examination was suggestive of giant cell tumor (GCT). Because of complete intralesional tumor excision and fear of post-radiation osteonecrosis of bone used for delayed bony union, a conservative approach was used, and radiation therapy was not given. After one year of follow-up patient is doing well without any recurrence of the tumor and is ambulant with support. GCT of dorsal vertebral body is an uncommon entity and total en bloc excision is difficult. Therefore, the treatment strategy is not well-defined. We discuss in brief about incidence, presentation and various treatment modalities available for spinal GCT. |
format | Online Article Text |
id | pubmed-3777315 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37773152013-09-30 Giant cell tumor of dorsal vertebral body Redhu, Rakesh Poonia, Rajpal J Craniovertebr Junction Spine Case Report A 30-year-old female patient presented with complaints of backache, weakness in both lower limbs and bladder/bowel dysfunction. Imaging showed an osteolytic lesion at tenth dorsal (D10) vertebra with anterior compression on the spinal cord. Complete intralesional tumor excision with reconstruction was carried out using the anterolateral extrapleural approach. Histopathological examination was suggestive of giant cell tumor (GCT). Because of complete intralesional tumor excision and fear of post-radiation osteonecrosis of bone used for delayed bony union, a conservative approach was used, and radiation therapy was not given. After one year of follow-up patient is doing well without any recurrence of the tumor and is ambulant with support. GCT of dorsal vertebral body is an uncommon entity and total en bloc excision is difficult. Therefore, the treatment strategy is not well-defined. We discuss in brief about incidence, presentation and various treatment modalities available for spinal GCT. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3777315/ /pubmed/24082687 http://dx.doi.org/10.4103/0974-8237.116542 Text en Copyright: © Journal of Craniovertebral Junction and Spine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Redhu, Rakesh Poonia, Rajpal Giant cell tumor of dorsal vertebral body |
title | Giant cell tumor of dorsal vertebral body |
title_full | Giant cell tumor of dorsal vertebral body |
title_fullStr | Giant cell tumor of dorsal vertebral body |
title_full_unstemmed | Giant cell tumor of dorsal vertebral body |
title_short | Giant cell tumor of dorsal vertebral body |
title_sort | giant cell tumor of dorsal vertebral body |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777315/ https://www.ncbi.nlm.nih.gov/pubmed/24082687 http://dx.doi.org/10.4103/0974-8237.116542 |
work_keys_str_mv | AT redhurakesh giantcelltumorofdorsalvertebralbody AT pooniarajpal giantcelltumorofdorsalvertebralbody |