A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer

According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent bre...

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Detalles Bibliográficos
Autores principales: Chen, Li-Sha, Wang, An-Xin, Dong, Bing, Pu, Ke-Feng, Yuan, Li-Hua, Zhu, Yi-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777459/
https://www.ncbi.nlm.nih.gov/pubmed/22507219
http://dx.doi.org/10.5732/cjc.011.10444
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author Chen, Li-Sha
Wang, An-Xin
Dong, Bing
Pu, Ke-Feng
Yuan, Li-Hua
Zhu, Yi-Min
author_facet Chen, Li-Sha
Wang, An-Xin
Dong, Bing
Pu, Ke-Feng
Yuan, Li-Hua
Zhu, Yi-Min
author_sort Chen, Li-Sha
collection PubMed
description According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent breakthroughs that have improved our understanding of cancer stem cells, and we discuss the therapeutic strategy of targeting cancer stem cells, a promising future direction for cancer stem cell research.
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spelling pubmed-37774592013-12-11 A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer Chen, Li-Sha Wang, An-Xin Dong, Bing Pu, Ke-Feng Yuan, Li-Hua Zhu, Yi-Min Chin J Cancer Review According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent breakthroughs that have improved our understanding of cancer stem cells, and we discuss the therapeutic strategy of targeting cancer stem cells, a promising future direction for cancer stem cell research. Sun Yat-sen University Cancer Center 2012-12 /pmc/articles/PMC3777459/ /pubmed/22507219 http://dx.doi.org/10.5732/cjc.011.10444 Text en Chinese Journal of Cancer http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.
spellingShingle Review
Chen, Li-Sha
Wang, An-Xin
Dong, Bing
Pu, Ke-Feng
Yuan, Li-Hua
Zhu, Yi-Min
A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer
title A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer
title_full A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer
title_fullStr A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer
title_full_unstemmed A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer
title_short A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer
title_sort new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777459/
https://www.ncbi.nlm.nih.gov/pubmed/22507219
http://dx.doi.org/10.5732/cjc.011.10444
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