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Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases
Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with high local invasiveness. To date, there is no consensus on the imaging characteristics of NACC. To address this, we retrospectively reviewed 10 cases of NACC and summarized the magnetic resonance imaging (MRI) features. MR imag...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sun Yat-sen University Cancer Center
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777462/ https://www.ncbi.nlm.nih.gov/pubmed/22200180 http://dx.doi.org/10.5732/cjc.011.10242 |
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author | Liu, Xue-Wen Xie, Chuan-Miao Li, Hui Zhang, Rong Geng, Zhi-Jun Mo, Yun-Xian Zhao, Jing Cai, Mu-Yan Lv, Yan-Chun Wu, Pei-Hong |
author_facet | Liu, Xue-Wen Xie, Chuan-Miao Li, Hui Zhang, Rong Geng, Zhi-Jun Mo, Yun-Xian Zhao, Jing Cai, Mu-Yan Lv, Yan-Chun Wu, Pei-Hong |
author_sort | Liu, Xue-Wen |
collection | PubMed |
description | Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with high local invasiveness. To date, there is no consensus on the imaging characteristics of NACC. To address this, we retrospectively reviewed 10 cases of NACC and summarized the magnetic resonance imaging (MRI) features. MR images of 10 patients with histologically validated NACC were reviewed by two experienced radiologists. The location, shape, margin, signal intensity, lesion texture, contrast enhancement patterns, local invasion, and cervical lymphadenopathy of all tumors were evaluated. Clinical and pathologic records were also reviewed. No patients were positive for antibodies against Epstein-Barr virus (EBV). The imaging patterns of primary tumors were classified into two types as determined by location, shape, and margin. Of all patients, 7 had tumors with a type 1 imaging pattern and 3 had tumors with a type 2 imaging pattern. The 4 tubular NACCs were all homogeneous tumors, whereas 3 (60%) of 5 cribriform NACCs and the sole solid NACC were heterogeneous tumors with separations or central necrosis on MR images. Five patients had perineural infiltration and intracranial involvement, and only 2 had cervical lymphadenopathy. Based on these results, we conclude that NACC is a local, aggressive neoplasm that is often negative for EBV infection and associated with a low incidence of cervical lymphadenopathy. Furthermore, MRI features of NACC vary in locations and histological subtypes. |
format | Online Article Text |
id | pubmed-3777462 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Sun Yat-sen University Cancer Center |
record_format | MEDLINE/PubMed |
spelling | pubmed-37774622013-12-11 Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases Liu, Xue-Wen Xie, Chuan-Miao Li, Hui Zhang, Rong Geng, Zhi-Jun Mo, Yun-Xian Zhao, Jing Cai, Mu-Yan Lv, Yan-Chun Wu, Pei-Hong Chin J Cancer Original Article Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with high local invasiveness. To date, there is no consensus on the imaging characteristics of NACC. To address this, we retrospectively reviewed 10 cases of NACC and summarized the magnetic resonance imaging (MRI) features. MR images of 10 patients with histologically validated NACC were reviewed by two experienced radiologists. The location, shape, margin, signal intensity, lesion texture, contrast enhancement patterns, local invasion, and cervical lymphadenopathy of all tumors were evaluated. Clinical and pathologic records were also reviewed. No patients were positive for antibodies against Epstein-Barr virus (EBV). The imaging patterns of primary tumors were classified into two types as determined by location, shape, and margin. Of all patients, 7 had tumors with a type 1 imaging pattern and 3 had tumors with a type 2 imaging pattern. The 4 tubular NACCs were all homogeneous tumors, whereas 3 (60%) of 5 cribriform NACCs and the sole solid NACC were heterogeneous tumors with separations or central necrosis on MR images. Five patients had perineural infiltration and intracranial involvement, and only 2 had cervical lymphadenopathy. Based on these results, we conclude that NACC is a local, aggressive neoplasm that is often negative for EBV infection and associated with a low incidence of cervical lymphadenopathy. Furthermore, MRI features of NACC vary in locations and histological subtypes. Sun Yat-sen University Cancer Center 2012-01 /pmc/articles/PMC3777462/ /pubmed/22200180 http://dx.doi.org/10.5732/cjc.011.10242 Text en Chinese Journal of Cancer http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission. |
spellingShingle | Original Article Liu, Xue-Wen Xie, Chuan-Miao Li, Hui Zhang, Rong Geng, Zhi-Jun Mo, Yun-Xian Zhao, Jing Cai, Mu-Yan Lv, Yan-Chun Wu, Pei-Hong Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases |
title | Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases |
title_full | Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases |
title_fullStr | Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases |
title_full_unstemmed | Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases |
title_short | Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases |
title_sort | nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777462/ https://www.ncbi.nlm.nih.gov/pubmed/22200180 http://dx.doi.org/10.5732/cjc.011.10242 |
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