A facile, branched DNA assay to quantitatively measure glucocorticoid receptor auto-regulation in T-cell acute lymphoblastic leukemia

Glucocorticoid (GC) steroid hormones are used to treat acute lymphoblastic leukemia (ALL) because of their pro-apoptotic effects in hematopoietic cells. However, not all leukemia cells are sensitive to GC, and no assay to stratify patients is available. In the GC-sensitive T-cell ALL cell line CEM-C...

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Detalles Bibliográficos
Autores principales: Schwartz, Jason R., Sarvaiya, Purvaba J., Leiva, Lily E., Velez, Maria C., Singleton, Tammuella C., Yu, Lolie C., Vedeckis, Wayne V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777508/
https://www.ncbi.nlm.nih.gov/pubmed/22739263
http://dx.doi.org/10.5732/cjc.012.10044

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