Amoeboid T lymphocytes Require the Septin Cytoskeleton for Cortical Integrity and Persistent Motility

The systems that refine actomyosin forces during motility remain poorly understood. Septins assemble on the T cell cortex and are enriched at the mid-zone in filaments. Septin knockdown causes membrane blebbing, excess leading edge protrusions, and lengthening of the trailingedge uropod. The associa...

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Detalles Bibliográficos
Autores principales: Tooley, Aaron J., Gilden, Julia, Jacobelli, Jordan, Beemiller, Peter, Trimble, William S., Kinoshita, Makoto, Krummel, Matthew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777658/
https://www.ncbi.nlm.nih.gov/pubmed/19043408
http://dx.doi.org/10.1038/ncb1808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777658/
https://www.ncbi.nlm.nih.gov/pubmed/19043408
http://dx.doi.org/10.1038/ncb1808

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