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Amoeboid T lymphocytes Require the Septin Cytoskeleton for Cortical Integrity and Persistent Motility
The systems that refine actomyosin forces during motility remain poorly understood. Septins assemble on the T cell cortex and are enriched at the mid-zone in filaments. Septin knockdown causes membrane blebbing, excess leading edge protrusions, and lengthening of the trailingedge uropod. The associa...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777658/ https://www.ncbi.nlm.nih.gov/pubmed/19043408 http://dx.doi.org/10.1038/ncb1808 |