Lipidated Dengue-2 Envelope Protein Domain III Independently Stimulates Long-Lasting Neutralizing Antibodies and Reduces the Risk of Antibody-Dependent Enhancement

BACKGROUND: Dengue virus is a mosquito-transmitted virus that can cause self-limiting dengue fever, severe life-threatening dengue hemorrhagic fever and dengue shock syndrome. The existence of four serotypes of dengue virus has complicated the development of an effective and safe dengue vaccine. Rec...

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Detalles Bibliográficos
Autores principales: Chiang, Chen-Yi, Pan, Chien-Hsiung, Hsieh, Chun-Hsiang, Tsai, Jy-Ping, Chen, Mei-Yu, Liu, Hsueh-Hung, Liu, Shih-Jen, Chong, Pele, Leng, Chih-Hsiang, Chen, Hsin-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777875/
https://www.ncbi.nlm.nih.gov/pubmed/24069487
http://dx.doi.org/10.1371/journal.pntd.0002432

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