Claudin-3 Overexpression Increases the Malignant Potential of Colorectal Cancer Cells: Roles of ERK1/2 and PI3K-Akt as Modulators of EGFR signaling

The altered expressions of claudin proteins have been reported during the tumorigenesis of colorectal cancer. However, the molecular mechanisms that regulate these events in this cancer type are poorly understood. Here, we report that epidermal growth factor (EGF) increases the expression of claudin...

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Detalles Bibliográficos
Autores principales: de Souza, Waldemir F., Fortunato-Miranda, Natalia, Robbs, Bruno K., de Araujo, Wallace M., de-Freitas-Junior, Julio C., Bastos, Lilian G., Viola, João P. B., Morgado-Díaz, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777902/
https://www.ncbi.nlm.nih.gov/pubmed/24069372
http://dx.doi.org/10.1371/journal.pone.0074994

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