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Collective Dynamics Underlying Allosteric Transitions in Hemoglobin
Hemoglobin is the prototypic allosteric protein. Still, its molecular allosteric mechanism is not fully understood. To elucidate the mechanism of cooperativity on an atomistic level, we developed a novel computational technique to analyse the coupling of tertiary and quaternary motions. From Molecul...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777908/ https://www.ncbi.nlm.nih.gov/pubmed/24068910 http://dx.doi.org/10.1371/journal.pcbi.1003232 |