Limited Agreement of Independent RNAi Screens for Virus-Required Host Genes Owes More to False-Negative than False-Positive Factors

Systematic, genome-wide RNA interference (RNAi) analysis is a powerful approach to identify gene functions that support or modulate selected biological processes. An emerging challenge shared with some other genome-wide approaches is that independent RNAi studies often show limited agreement in thei...

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Detalles Bibliográficos
Autores principales: Hao, Linhui, He, Qiuling, Wang, Zhishi, Craven, Mark, Newton, Michael A., Ahlquist, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777922/
https://www.ncbi.nlm.nih.gov/pubmed/24068911
http://dx.doi.org/10.1371/journal.pcbi.1003235

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