Cargando…

Sonic Hedgehog Mediates the Proliferation and Recruitment of Transformed Mesenchymal Stem Cells to the Stomach

Studies using Helicobacter-infected mice show that bone marrow-derived mesenchymal stem cells (MSCs) can repopulate the gastric epithelium and promote gastric cancer progression. Within the tumor microenvironment of the stomach, pro-inflammatory cytokine interferon-gamma (IFNγ) and Sonic hedgehog (S...

Descripción completa

Detalles Bibliográficos
Autores principales: Donnelly, Jessica M., Chawla, Ambreesh, Houghton, JeanMarie, Zavros, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777931/
https://www.ncbi.nlm.nih.gov/pubmed/24069395
http://dx.doi.org/10.1371/journal.pone.0075225