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Sonic Hedgehog Mediates the Proliferation and Recruitment of Transformed Mesenchymal Stem Cells to the Stomach

Studies using Helicobacter-infected mice show that bone marrow-derived mesenchymal stem cells (MSCs) can repopulate the gastric epithelium and promote gastric cancer progression. Within the tumor microenvironment of the stomach, pro-inflammatory cytokine interferon-gamma (IFNγ) and Sonic hedgehog (S...

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Detalles Bibliográficos
Autores principales:	Donnelly, Jessica M., Chawla, Ambreesh, Houghton, JeanMarie, Zavros, Yana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777931/ https://www.ncbi.nlm.nih.gov/pubmed/24069395 http://dx.doi.org/10.1371/journal.pone.0075225

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