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Differential Protective Effects of Exenatide, an Agonist of GLP-1 Receptor and Piragliatin, a Glucokinase Activator in Beta Cell Response to Streptozotocin-Induced and Endoplasmic Reticulum Stresses

BACKGROUND: Agonists of glucagon-like peptide-1 receptor (GLP-1R) and glucokinase activators (GKA) act as antidiabetic agents by their ability protect beta cells, and stimulate insulin secretion. Oxidative and endoplasmic reticulum (ER) stresses aggravate type 2 diabetes by causing beta cell loss. I...

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Detalles Bibliográficos
Autores principales:	Kim, Mi-Kyung, Cho, Jin-Hwan, Lee, Jae-Jin, Cheong, Ye-Hwang, Son, Moon-Ho, Lee, Kong-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777936/ https://www.ncbi.nlm.nih.gov/pubmed/24069189 http://dx.doi.org/10.1371/journal.pone.0073340

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