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Intranasal Delivery of Plasma and Platelet Growth Factors Using PRGF-Endoret System Enhances Neurogenesis in a Mouse Model of Alzheimer’s Disease
Neurodegeneration together with a reduction in neurogenesis are cardinal features of Alzheimer’s disease (AD) induced by a combination of toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration of these was assessed with diverse neurotrophins in experimental therapeutic appro...
Autores principales: | Anitua, Eduardo, Pascual, Consuelo, Pérez-Gonzalez, Rocio, Antequera, Desiree, Padilla, Sabino, Orive, Gorka, Carro, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777974/ https://www.ncbi.nlm.nih.gov/pubmed/24069173 http://dx.doi.org/10.1371/journal.pone.0073118 |
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