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Modulation of Mononuclear Phagocyte Inflammatory Response by Liposome-Encapsulated Voltage Gated Sodium Channel Inhibitor Ameliorates Myocardial Ischemia/Reperfusion Injury in Rats

BACKGROUND: Emerging evidence shows that anti-inflammatory strategies targeting inflammatory monocyte subset could reduce excessive inflammation and improve cardiovascular outcomes. Functional expression of voltage-gated sodium channels (VGSCs) have been demonstrated in monocytes and macrophages. We...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Luo, Yue-Chen, Ji, Wen-Jie, Zhang, Li, Dong, Yan, Ge, Lan, Lu, Rui-Yi, Sun, Hai-Ying, Guo, Zao-Zeng, Yang, Guo-Hong, Jiang, Tie-Min, Li, Yu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777990/
https://www.ncbi.nlm.nih.gov/pubmed/24069305
http://dx.doi.org/10.1371/journal.pone.0074390