MicroRNA-17-92, a Direct Ap-2α Transcriptional Target, Modulates T-Box Factor Activity in Orofacial Clefting

Among the most common human congenital anomalies, cleft lip and palate (CL/P) affects up to 1 in 700 live births. MicroRNA (miR)s are small, non-coding RNAs that repress gene expression post-transcriptionally. The miR-17-92 cluster encodes six miRs that have been implicated in human cancers and hear...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Bai, Yan, Li, Hong, Greene, Stephanie B., Klysik, Elzbieta, Yu, Wei, Schwartz, Robert J., Williams, Trevor J., Martin, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777996/
https://www.ncbi.nlm.nih.gov/pubmed/24068957
http://dx.doi.org/10.1371/journal.pgen.1003785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777996/
https://www.ncbi.nlm.nih.gov/pubmed/24068957
http://dx.doi.org/10.1371/journal.pgen.1003785

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