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Genotype-Environment Interactions Reveal Causal Pathways That Mediate Genetic Effects on Phenotype
Unraveling the molecular processes that lead from genotype to phenotype is crucial for the understanding and effective treatment of genetic diseases. Knowledge of the causative genetic defect most often does not enable treatment; therefore, causal intermediates between genotype and phenotype constit...
Autores principales: | Gagneur, Julien, Stegle, Oliver, Zhu, Chenchen, Jakob, Petra, Tekkedil, Manu M., Aiyar, Raeka S., Schuon, Ann-Kathrin, Pe'er, Dana, Steinmetz, Lars M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778020/ https://www.ncbi.nlm.nih.gov/pubmed/24068968 http://dx.doi.org/10.1371/journal.pgen.1003803 |
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