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The effects of radiation on antitumor efficacy of an oncolytic adenovirus vector in the Syrian hamster model

We report that radiation enhances the antitumor efficacy of the oncolytic adenovirus vector VRX-007 in Syrian hamster tumors. We used tumor-specific irradiation of subcutaneous tumors and compared treatment options of radiation alone or combined with VRX-007 and cyclophosphamide (CP). Radiation ther...

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Detalles Bibliográficos
Autores principales: Young, Brittany A., Spencer, Jacqueline F., Ying, Baoling, Toth, Karoly, Wold, William S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778061/
https://www.ncbi.nlm.nih.gov/pubmed/23928730
http://dx.doi.org/10.1038/cgt.2013.50